Does a four-divergence extra term in a Lagrangian density matter to the field equations?

Greiner in his book "Field Quantization" page 173, eq.(7.11) did this calculation:

${\mathcal L}^\prime=-\frac{1}{2}\partial_\mu A_\nu\partial^\mu A^\nu+\frac{1}{2}\partial_\mu A_\nu\partial^\nu A^\mu-\frac{1}{2}\partial_\mu A^\mu\partial_\nu A^\nu$
$\space\space\space\space=-\frac{1}{2}\partial_\mu A_\nu\partial^\mu A^\nu+\frac{1}{2}\partial_\mu[A_\nu(\partial^\nu A^\mu)-(\partial_\nu A^\nu) A^\mu]$

The last term is a four-divergence which has no influence on the field equations. Thus the dynamics of the electromagnetic field (in the Lorentz gauge) can be described by the simple Lagrangian

${\mathcal L}^{\prime\prime}=-\frac{1}{2}\partial_\mu A_\nu\partial^\mu A^\nu$

Yes, if it is a four-divergence of a vector whose 0-component doesn't contain time derivatives of the field, indeed according to the variational principle this four-divergence will not influence the field equation.

And actually I calculated the time-derivative dependence of 0-component of $[A_\nu(\partial^\nu A^\mu)-(\partial_\nu A^\nu) A^\mu]$, in which only $[A_0(\partial^0 A^0)-(\partial_0 A^0) A^0]$ could possibly contain time-derivative, which vanishes fortunately, so whatever the general case it doesn't matter in this present case.

But how can he seem to claim that it holds for a general four-divergence term,The last term is a four-divergence which has no influence on the field equations?

EDIT:
I only assumed the boundary condition to be $A^\mu=0$ at spatial infinity, not at time infinity. And the variation of the action $S = \int_{t_1}^{t_2}L \, dt$ is due to the variation of fields which vanish at time, $\delta A^\mu(\mathbf x,t_1)=\delta A^\mu(\mathbf x,t_2)=0$, not having the knowledge of $\delta \dot A^\mu(\mathbf x,t_1)$ and $\delta \dot A^\mu(\mathbf x,t_2)$, which don't vanish generally, so the four-divergence term will in general contribute to the action, $$\delta S_j=\delta \int_{t_1}^{t_2}dt\int d^3\mathbf x \partial_\mu j(A(x),\nabla A(x),\dot A(x))^\mu =\delta \int_{t_1}^{t_2}dt\int d^3\mathbf x \dot j^0 =\int d^3\mathbf x [\delta j(\mathbf x, t_2)^0-\delta j(\mathbf x, t_1)^0]$$which does not vanish in general!